Deborah DeRyckere : rechercher sur Z-Library

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1

Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents

Margaret E. Macy, Deborah DeRyckere, Lia Gore

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 436 KB

english, 2012

2

Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

Liu, Jing, Yang, Chao, Simpson, Catherine, DeRyckere, Deborah, Van Deusen, Amy, Miley, Michael J., Kireev, Dmitri, Norris-Drouin, Jacqueline, Sather, Susan, Hunter, Debra

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2012

3

Identification and characterization of transcription factor target genes using gene-targeted mice

Deborah DeRyckere, James DeGregori

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 524 KB

english, 2002

4

Structure and Function of Cdc6/Cdc18: Implications for Origin Recognition and Checkpoint Control

Jinyu Liu, Cheryl L. Smith, Deborah DeRyckere, Kristen DeAngelis, G.Steven Martin, James M. Berger

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2000

5

UNC1062, a new and potent Mer inhibitor

Liu, Jing, Zhang, Weihe, Stashko, Michael A., DeRyckere, Deborah, Cummings, Christopher T., Hunter, Debra, Yang, Chao, Jayakody, Chatura N., Cheng, Nancy, Simpson, Catherine, Norris-Drouin, Jacqueline

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2013

6

Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis

Zhang, Weihe, McIver, Andrew L., Stashko, Michael A., DeRyckere, Deborah, Branchford, Brian R., Hunter, Debra, Kireev, Dmitri, Miley, Michael J., Norris-Drouin, Jacqueline, Stewart, Wendy M., Lee, Min

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.67 MB

english, 2013

7

Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors

Zhang, Weihe, Zhang, Dehui, Stashko, Michael A., DeRyckere, Deborah, Hunter, Debra, Kireev, Dmitri, Miley, Michael J., Cummings, Christopher, Lee, Minjung, Norris-Drouin, Jacqueline, Stewart, Wendy M.

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 4.96 MB

english, 2013

8

Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis

Zhang, Weihe, McIver, Andrew L., Stashko, Michael A., DeRyckere, Deborah, Branchford, Brian R., Hunter, Debra, Kireev, Dmitri, Miley, Michael J., Norris-Drouin, Jacqueline, Stewart, Wendy M., Lee, Min

Journal:

Journal of Medicinal Chemistry

Année:

2014

Fichier:

PDF, 2.48 MB

2014

9

UNC2025 , a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor

Zhang, Weihe, DeRyckere, Deborah, Hunter, Debra, Liu, Jing, Stashko, Michael A., Minson, Katherine A., Cummings, Christopher T., Lee, Minjung, Glaros, Trevor G., Newton, Dianne L., Sather, Susan, Zhan

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2014

10

Correction to Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors

Zhang, Weihe, Zhang, Dehui, Stashko, Michael A., DeRyckere, Deborah, Hunter, Debra, Kireev, Dmitri, Miley, Michael J., Cummings, Christopher, Lee, Minjung, Norris-Drouin, Jacqueline, Stewart, Wendy M.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Fichier:

PDF, 1.33 MB

2014

11

Correction to Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

Liu, Jing, Yang, Chao, Simpson, Catherine, DeRyckere, Deborah, Deusen, Amy Van, Miley, Michael J., Kireev, Dmitri, Norris-Drouin, Jacqueline, Sather, Susan, Hunter, Debra, Korboukh, Victoria K., Patel

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Fichier:

PDF, 854 KB

2014

12

The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer

Graham, Douglas K., DeRyckere, Deborah, Davies, Kurtis D., Earp, H. Shelton

Journal:

Nature Reviews Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2014

13

Gene Conversion in Neisseria gonorrhoeae: Evidence for Its Role in Pilus Antigenic Variation

Qian Yun Zhang, Deborah DeRyckere, Peter Lauer and Michael Koomey

Journal:

Proceedings of the National Academy of Sciences

Année:

1992

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1992

14

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors

Wang, Xiaodong, Liu, Jing, zhang, weihe, Stashko, Michael A., Nichols, James, Miley, Michael J., Norris-Drouin, Jacqueline L., Chen, Zhilong, Machius, Mischa, DeRyckere, Deborah, Wood, Edgar R., Graha

Journal:

ACS Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 528 KB

english, 2016

15

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors

McIver, Andrew L., Zhang, Weihe, Liu, Qingyang, Jiang, Xinpeng, Stashko, Michael A., Nichols, James, Miley, Michael J., Norris-Drouin, Jacqueline, Machius, Mischa, DeRyckere, Deborah, Wood, Edgar, Gra

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2017

16

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Schlegel, Jennifer, Sambade, Maria J., Sather, Susan, Moschos, Stergios J., Tan, Aik-Choon, Winges, Amanda, DeRyckere, Deborah, Carson, Craig C., Trembath, Dimitri G., Tentler, John J., Eckhardt, S. G

Journal:

Journal of Clinical Investigation

Année:

2013

Langue:

english

Fichier:

PDF, 4.06 MB

english, 2013

17

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Schlegel, Jennifer, Sambade, Maria J, Sather, Susan, Moschos, Stergios J, Tan, Aik-choon, Winges, Amanda, Deryckere, Deborah, Carson, Craig C, Trembath, Dimitri G, Tentler, John J, Eckhardt, S Gail, K

Année:

2013

Langue:

english

Fichier:

PDF, 4.06 MB

english, 2013

18

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Christoph, Sandra, Lee-Sherick, Alisa B., Sather, Susan, DeRyckere, Deborah, Graham, Douglas K.

Journal:

Journal of Visualized Experiments

Année:

2013

Langue:

english

Fichier:

PDF, 382 KB

english, 2013

19

Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus

Migdall-Wilson, Justine, Bates, Christine, Schlegel, Jennifer, Brandão, Luis, Linger, Rachel M. A., DeRyckere, Deborah, Graham, Douglas K., Agoulnik, Irina

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 703 KB

english, 2012

20

Targeting the TAM Receptors in Leukemia

Huey, Madeline, Minson, Katherine, Earp, H., DeRyckere, Deborah, Graham, Douglas

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

21

MERTK promotes resistance to irreversible EGFR tyrosine kinase inhibitors in non-small cell lung cancers expressing wild-type EGFR-family members

Yan, Dan, Parker, Rebecca E, Wang, Xiaodong, Frye, Stephen V, Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K

Journal:

Clinical Cancer Research

Année:

2018

Langue:

english

Fichier:

PDF, 12.25 MB

english, 2018

22

Highly selective MERTK inhibitors achieved by a single methyl group

Zhao, Jichen, Zhang, Dehui, zhang, weihe, Stashko, Michael A., DeRyckere, Deborah, Vasileiadi, Eleana, Parker, Rebecca E, Hunter, Debra, Liu, Qingyang, Zhang, Yuewei, Norris-Drouin, Jacqueline L., Li,

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 618 KB

english, 2018

23

The Current State of FLT3 Inhibition in Acute Myeloid Leukemia – Pitfalls and Promises

Minson, Katherine A, DeRyckere, Deborah, Graham, Douglas K

Journal:

Journal of Cell Signaling

Année:

2017

Langue:

english

Fichier:

PDF, 492 KB

english, 2017

24

The Emerging Role of TYRO3 as a Therapeutic Target in Cancer

Smart, Sherri, Vasileiadi, Eleana, Wang, Xiaodong, DeRyckere, Deborah, Graham, Douglas

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2018

25

HG-123AN EPIGENOMIC SCREEN REVEALS THE CHROMATIN REMODELING PROTEIN BPTF AS A DRIVER OF HIGH-GRADE GLIOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA GROWTH IN VITRO AND IN VIVO

Green, Adam, Flannery, Patrick, DeSisto, John, Lemieux, Madeleine, Ramkissoon, Shak, Jones, Kristen, Perry, Jennifer, Hubbell-Engler, Benjamin, DeRyckere, Deborah, Venkataraman, Sujatha, Foreman, Nich

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 61 KB

english, 2016

26

MERTK in cancer therapy: Targeting the receptor tyrosine kinase in tumor cells and the immune system

Huelse, Justus, Fridlyand, Diana, Earp, Shelton, DeRyckere, Deborah, Graham, Douglas K.

Journal:

Pharmacology & Therapeutics

Année:

2020

Fichier:

PDF, 13.32 MB

2020